• RNase Inhibitor sale Although the presence of calcium in RHA

  2020-09-23

  

  Although the presence of calcium in RHA-P active site is confirmed by the homology modeling, some additional observations can be made following the metal depletion and reconstitution experiments performed on RHA-Phis. EDTA-treated RHA-Phis recovers its activity in the presence of divalent cations su

• br Perspective and conclusion Collagen Toolkits

  2020-09-23

  

  Perspective and conclusion Collagen Toolkits II and III have been used to determine the Triptolide for DDR1 and DDR2, and the main binding site is the GVM-GFO motif [103,108]. The co-crystal structure of the DS domain of human DDR2 bound to a synthetic collagen-like peptide containing the GVM-GF

• To elucidate whether the impact of hypoxia on

  2020-09-23

  

  To elucidate whether the impact of hypoxia on EGFR expression is cell context specific or culturing density dependent, we chose the following cancer cysteine protease driven by EGFR and evaluated the EGFR expression after hypoxia treatment at different culturing density: a highly aggressive and poo

• br Materials and methods br Results br

  2020-09-23

  

  Materials and methods Results Discussion Plg plays important roles in various physiological processes, such as fibrinolysis, proteolysis, cell migration, differentiation, tissue remodeling, and inflammation [6], [7], [8]. We herein found that Plg deficiency enhanced insulin secretion, and w

• AMPHs facilitate dopamine release which further triggers dop

  2020-09-23

  

  AMPHs facilitate dopamine release, which further triggers dopamine depletion [72]. Indeed, we observed that repeated treatment of MPA significantly inhibited TH-, DAT-, and VMAT-2 levels. Since DAT and VMAT-2 are important for dopaminergic terminal markers [10], their decreases suggest that MPA-indu

• br Experimental Procedures DNA synthesis reagents were

  2020-09-23

  

  Experimental Procedures DNA synthesis reagents were purchased from Glen Research (Sterling, VA). A solution of 0.1 M triethylamine acetate (TEAA) (pH 6.5) was used as HPLC buffer A, and HPLC-grade acetonitrile from Oceanpak (Sweden) was used as HPLC buffer B. All other chemicals were obtained fro

• l glycine br STAR Methods br Acknowledgments We are

  2020-09-22

  

  STAR★Methods Acknowledgments We are grateful to Matthias Mayer at ZMBH in Heidelberg for access to his CD-spectrometer and his help in data interpretation. Technical support by Wolfgang Weinig is gratefully acknowledged. This project was financially supported by the European Union as part of t

• Q-VD Oph br Materials and Methods br

  2020-09-22

  

  Materials and Methods Results Discussion HSCs have been identified as major collagen-producing Q-VD Oph in the injured liver (1), and activation of HSCs has become the central link for liver fibrosis (2). The factors that regulate the biological behavior of HSCs include soluble regulatory f

• Members of the Nudix family typically contain

  2020-09-22

  

  Members of the Nudix family typically contain a 23-amino-acid sequence (Nudix box) of GxExREUxEExGU, where U is usually Ile, Leu, or Val and x represents any amino acid. The EUxEE core residues serve as anchors for an Mg ligand that associates with a characteristic pyrophosphate linkage that is comm

• Despite the significant associations between

  2020-09-22

  

  Despite the significant associations between TNF-α and TRAIL in our results, the use of a single top cytokine in predicting sPTB is limited, and the previous study using the specific candidate cytokines failed to accurately predict the risk for sPTB in asymptomatic women, with AUC ranged from 0.48 t

• In conclusion by investigating the

  2020-09-22

  

  In conclusion, by investigating the cysteine protease transcriptome in soybean nodules, we found a number of cysteine proteases belonging to the C1 and C13 families strongly up-regulated following drought exposure such as C1 cysteine protease Glyma.14G085800 and C13 cysteine proteases Glyma.17G23070

• In conclusion we developed a new

  2020-09-22

  

  In conclusion, we developed a new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model that can be useful for screening both CysLT2 receptor and CysLT1/2 receptor antagonists. In addition, we have shown that the dual CysLT1/2 receptor antagonist ONO-6950 can exert protective effect agai

• Elacridar Similarly to the chemokine CCL the

  2020-09-22

  

  Similarly to the chemokine CCL-5, the level of the chemokine SDF-1 in the groups of individuals with APD did not differ from its level in the control group. However, a slight increase in the level of this chemokine was recorded in the group of women and men with APD and PTSD as compared with the cor

• Self Determination Theory SDT as described by Ryan and Deci

  2020-09-22

  

  Self-Determination Theory (SDT), as described by Ryan and Deci (2000) is “an approach to human motivation and personality that uses traditional empirical methods while employing an organismic metatheory highlighting the importance of humans\' evolved inner resources for personality development and b

• br Introduction Al Awqati and his colleagues using R

  2020-09-22

  

  Introduction Al Awqati and his colleagues using R(+)-methylindazone, R(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)-oxy] acetic GDC-0084 (IAA-94) (Landry et al., 1987) isolated the first chloride intracellular ion channel (CLIC) proteins (p64) from bovine kidney cort

15560 records 776/1038 page Previous Next First page 上5页 776777778779780 下5页 Last page