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In conclusion by investigating the
2021-07-13

In conclusion, by investigating the cysteine protease transcriptome in soybean nodules, we found a number of cysteine proteases belonging to the C1 and C13 families strongly up-regulated following drought exposure such as C1 cysteine protease Glyma.14G085800 and C13 cysteine proteases Glyma.17G23070
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br Materials and methods Male Hartley guinea pigs
2021-07-13

Materials and methods Male Hartley guinea pigs (300–350g) were obtained from National Laboratory Animal Center, Taiwan. LTD4, LTC4, LTE4, LTB4, montelukast and BAY u9773 were purchased from Cayman Chemical, Ann Arbor, Michigan; Carbachol, atropine, l-serine, boric acid, l-cysteine and all buffer
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Based on our studies presented above atipamezole
2021-07-13

Based on our studies presented above, atipamezole can be used as a new in vitro and in vivo tool meclozine receptor as a pan-CYP inhibitor for CYP mediated metabolism study. It carries many unique characteristics compared to ABT which is currently being widely used for this purpose. These new chara
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vip receptor A summary of the drug
2021-07-13

A summary of the drug-CDK2/6/9 hydrophobic (Φ), hydrogen-bonding (H), and polar-bonding (P) interactions based upon the KLIFS residue numbers is provided in Table 5. The KLIFS system gives comparable residues from different vip receptor the same value [77], which facilitates comparisons among diffe
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br Neuroimaging Neuroimaging has not yet been systematically
2021-07-13

Neuroimaging Neuroimaging has not yet been systematically reported in individuals with CDD, although case reports document normal sevelamer hcl anatomy or less often, show cortical atrophy or T2 fluid-attenuated inversion recovery hyperintensities in the white matter.15, 17, 18, 19, 48, 52, 54, 5
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VEGF inhibition causes vascular regression and tissue hypoxi
2021-07-13

VEGF inhibition causes vascular regression and tissue hypoxia in tumor tissues and their surrounding healthy adipose tissues. In this regard, tumors in steatotic livers and adjacent to adipose tissues would experience more hypoxia than non-adipose tumors. Indeed, our present experimental results sup
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In we studied normal rational varieties X
2021-07-13

In [1] we studied normal, rational -varieties X of complexity one, where the latter means that X comes with an effective torus action such that holds. We showed that for affine X with and at most log terminal singularities, the iteration of Cox rings is possible. In the present article, we charac
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During the Lapita period in Tonga the Talasiu site would
2021-07-13

During the Lapita period in Tonga, the Talasiu site would have been an attractive location for human settlement as it overlooked an embayment holding large numbers of sessile and gregarious shellfish close to a fresh water solution channel, with gardening soils immediately inland. However, sea level
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Our results for imidacloprid were unexpected
2021-07-13

Our results for imidacloprid were unexpected: considering that imidacloprid (Im) is a neonicotinoid insecticide with a different mode of action (agonist of the nicotinic gedatolisib receptor) than OPs, we expected Es-ChE and T-ChE activity to be largely insensitive to changes in Im concentrations.
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The present study is the
2021-07-13

The present study is the first time to investigate the effect of piperine on intestinal sterol transporters and enzymes in the small intestine. NPC1L1 is a sterol transporter responsible for taking up cholesterol from the lumen to enterocytes (Davis et al., 2004). ACAT2 is an enzyme, which esterifie
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During mouse embryogenesis RLIM protein is
2021-07-13

During mouse embryogenesis, RLIM protein is detectable throughout preimplantation development, consistent with its functions in iXCI maintenance. However, in contrast to differentiating ESCs in culture (Figure 2A), RLIM protein levels are downregulated in nuclei of epiblast cells of implanting embry
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The nuclear receptor NR superfamily of ligand regulated tran
2021-07-13

The nuclear receptor (NR) superfamily of ligand regulated transcription factors has proven to be a rich source of targets for the development of therapeutics for a wide range of human diseases. The NR3B subfamily known as the estrogen-related receptor (ERRα[NR3B1], ERRβ[NR3B2] and ERRγ[NR3B3]) regul
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Introduction Psoriasis is a chronic
2021-07-13

Introduction Psoriasis is a chronic, recurrent and inflammatory skin disease, and it is characterized by erythema, skin hyperplasia, scales, and hyperproliferation of keratinocyte [1]. It is reported that the psoriasis occurrences are about 3% worldwide [2], but the number varies depending on ethni
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A key inciting event in atherosclerosis is the deposition of
2021-07-12

A key inciting event in atherosclerosis is the deposition of circulating low-density lipoprotein (LDL) in the subendothelial space of major arteries. In the subendothelium, native LDL is no longer protected by circulating antioxidants and is oxidatively modified to oxidized LDL (OxLDL) [5]. OxLDL is
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Despite the fact that the precise relevance
2021-07-12

Despite the fact that the precise relevance of Ube2E self-ubiquitination in vivo is still elusive, findings of Sarkari et al. do establish Ube2E1 ubiquitination in 5-moUTP [36]. In vivo self-ubiquitination of Ube2E1 is further supported by the high-throughput study aimed to identify all ubiquitinat
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